As a fully biodegradable dermal treatment, Regenerative# Biostimulator will gradually be broken down to calcium and phosphate ions and be absorbed by your body naturally over time.12-15
Yes, Regenerative# Biostimulator has received both U.S. FDA approval and EU CE mark.
Things to do
– Keep treated area cooled to prevent or reduce swelling16
– Avoid applying pressure for 12 to 24 hours
– Avoid extreme warmth or UV light
– Avoid make-up 12 hours after treatment
Things to note
– Avoid treatment if you have a skin infection16
– If you have a history of herpes, you may experience a herpes breakout after treatment16
– Regenerative# Biostimulator microspheres may be visible on X-rays and CT scans
Depending on the individual’s treatment area, age, skin type, lifestyle and metabolism, Regenerative# Biostimulator effects may last up to 2 years.17
Due to the safety and tolerability of Regenerative# Biostimulator, you will experience minimal to no downtime after treatment, allowing you to return to work quickly.17
Please consult your aesthetic physician for the possibility of combination treatments within the Merz Aesthetics portfolio, such as incobotulinum toxin A, MFU-V, and Cohesive Polydensified Matrix® hyaluronic acid filler.
Due to the safety and tolerability of Regenerative# Biostimulator, you will experience minimal to no downtime after treatment, allowing you to return to work quickly.17
Let us know if you have any queries and
we will get back to you shortly.
#Regenerative refers to the ability to stimulate the production of type I & III collagen, elastin and proteoglycans, as well as increase angiogenesis, cell proliferation and fibroblast contractility.1-8
References:
1. Goldie K. J Cosmet Dermatol. 2023 Mar;22 Suppl 1:1-7.
2. Corduff N. J Cosmet Dermatol. 2023 Mar;22 Suppl 1:8-14.
3. Amiri M, et al. Front Med (Lausanne). 2023 Jun 2;10:1195934.
4. Yutskovskaya Y, et al. J Drugs Dermatol. 2014 Sep;13(9):1047-52.
5. Yutskovskaya Y, et al. J Drugs Dermatol. 2017 Jan 1;16(1):68-74.
6. González N, Goldberg DJ. Dermatol Surg. 2019 Apr;45(4):547-551.
7. Kim J. Clin Cosmet Investig Dermatol. 2019 Oct 15;12:771-784.
8. Courderot-Masuyer C, et al. J Cosmet Dermatol. 2016 Sep;15(3):260-8.
9. Muti GF, et al. J Drugs Dermatol. 2015:14(9):948-54.
10. Chang JW, et al. J Craniofac Surg. 2020;31(1):e18–21.
11. van Loghem JV, et al. J Clin Aesthet Dermatol. 2015;8(1):38-49.
12. Marmur ES, et al. J Cosmet Laser Ther. 2004;6(4):223-6.
13. Lemperle G, et al. Aesthet Plast Surg. 2003;27(5):354-366.
14. Pavicic T. Clin Cosmet Investig Dermatol. 2015;8:19–25.
15. Chang JW, et al. J Craniofac Surg. 2020;31(1):e18–21.
16. Radiesse Instructions for use. Merz North America, Inc.
17. Bass LS, Smith S, Busso M, McClaren M. Aesthetic Surgery J. 2010; 30(2):235-238.
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